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Cryo-FIB/SEM Staff Scientist, CryoEM Facility
  • Job Number: 25802
  • Functional Area: Research - Scientific
  • Department: Biology
  • School Area: Science
  • Pay Range Minimum: $73,000
  • Pay Range Maximum: $111,000
  • Employment Type: Full-Time
  • Employment Category: Exempt
  • Visa Sponsorship Available: No
  • Schedule:
  • Pay Grade: No Grade


Posting Description

CRYO-FIB/SEM Staff Scientist, CryoEM Facility, Biology, to lead the adoption of next-generation plasma FIB milling and in situ structural biology as the primary expert for the newly installed HydraBio plasma FIB/SEM; advance cellular and tissue imaging by developing cryo-FIB/ET and volume EM workflows, including fluorescence-guided targeting, precision milling, and lift-out; provide user training, experimental design consultation, and troubleshooting; collaborate on sample preparation, tomography, and data reconstruction; and drive innovative method development and publications; oversee instrument calibration, vendor servicing, and facility infrastructure, including liquid nitrogen and data storage; represent the facility through tours, workshops, and scientific outreach, strengthening cryo-ET and volume EM research across the Cambridge/Boston community.

The full job description is available, here: https://acrobat.adobe.com/id/urn:aaid:sc:US:4001a239-70bd-4d68-837c-15d86f680ace

Job Requirements

REQUIRED: Master’s or Ph.D. in biochemistry, structural biology, biophysics, or a closely related discipline; demonstrated hands-on expertise in cryo-FIB milling technology and scanning electron microscopy (SEM); strong foundation in cryogenic sample preparation methods for cells or tissues; exceptional troubleshooting, organizational, and interpersonal skills; and strong commitment to collaborative problem-solving and mentoring a diverse scientific community. Single Particle Analysis (SPA) experience is not required for this role. PREFERRED: A minimum of four years of hands-on research experience in biological electron microscopy; experience with transmission electron microscopy (TEM), particularly with cryo-ET data collection setup on a Titan Krios; background in volume EM, sample lift-out techniques, or cryo-ET data processing workflows, including sub-tomogram averaging (STA); experience diagnosing and resolving FIB/SEM hardware or performance issues; or experience supporting users in a shared research facility.

Must have independent authorization to work in the US.  Visa sponsorship is not available.

Revised 6/29/2026